Kirby's Dream Land 3
In Kirby's Dream Land 3, Samus Aran wants Kirby to exterminate a horde of Metroids in exchange for a Heart Star. The Metroids are hard to kill, as you need Ice Kirby, for Ice is their only weakness, a reference to how they're killed in the Metroid games.
Super Smash Bros. Series
In the Super Smash Bros. series, Samus is a starting playable character in all 3 games. She hails from the Metroid series as the first and only playable character of it (not counting Zero Suit Samus, as she is just Samus without her powersuit and its moveset). She has projectile attacks such as her Charge Shot and Missiles that cover a wide range of space.
- The entire level of having to defeat all the Metroids was a reference to Metroid II, where Samus' mission is to destroy all the last Metroids on SR388. She awards you with her helmet off because since you've exterminated all the Metroids in the area, your mission is complete. In the Metroid games, when you get all the items fast enough, you get rewarded at the end by seeing Samus without her helmet or even her whole suit. This is basically the same concept.
- In Kirby Super Star and Kirby Super Star Ultra, a statue of Samus can appear while using the Stone ability.
- A treasure in The Great Cave Offensive, the Screw Attack, is an item Samus equips in the Metroid games to be able to spin rapidly in the air, reaching many places and destroying enemies upon contact.